Mosaic Genome Architecture of the Anopheles gambiae Species Complex

Mosaic Genome Architecture of the Anopheles gambiae Species Complex

BACKGROUND Attempts over the last three decades to reconstruct the phylogenetic history of the Anopheles gambiae species complex have been important for developing better strategies to control malaria transmission. METHODOLOGY We used fingerprint genotyping data from 414 field-collected female mosquitoes at 42 microsatellite loci to infer the evolutionary relationships of four species in the ...

Anopheles gambiae genome: completing the malaria triad.

T he genome sequence of Anopheles gambiae, the major mosquito vector of the malaria parasite Plasmodium falciparum, as well as analyses of its gene content and organization , are reported by several teams of investigators in this issue.* In addition, the sequence of the P. falciparum genome appears in this week's issue of Nature. The genomes of these two organisms, along with that of the human,...

Species Shifts in the Anopheles gambiae Complex: Do LLINs Successfully Control Anopheles arabiensis?

INTRODUCTION High coverage of conventional and long-lasting insecticide treated nets (ITNs and LLINs) in parts of E Africa are associated with reductions in local malaria burdens. Shifts in malaria vector species ratio have coincided with the scale-up suggesting that some species are being controlled by ITNs/LLINs better than others. METHODS Between 2005-2006 six experimental hut trials of IT...

Morphological Divergences in the Anopheles Gambiae Complex.

Cross-Species Y Chromosome Function Between Malaria Vectors of the Anopheles gambiae Species Complex

Y chromosome function, structure and evolution is poorly understood in many species, including the Anopheles genus of mosquitoes-an emerging model system for studying speciation that also represents the major vectors of malaria. While the Anopheline Y had previously been implicated in male mating behavior, recent data from the Anopheles gambiae complex suggests that, apart from the putative pri...